2007 Data mining Optimization Uncertainty 
The Unofficial Google Data Science Blog
APRIL 23, 2024
If the relationship of $X$ to $Y$ can be approximated as quadratic (or any polynomial), the objective and constraints as linear in $Y$, then there is a way to express the optimization as a quadratically constrained quadratic program (QCQP). Crucially, it takes into account the uncertainty inherent in our experiments.
The Unofficial Google Data Science Blog
JULY 22, 2020
For this reason we don’t report uncertainty measures or statistical significance in the results of the simulation. From a Bayesian perspective, one can combine joint posterior samples for $E[Y_i | T_i=t, E_i=j]$ and $P(E_i=j)$, which provides a measure of uncertainty around the estimate. 2] Scott, Steven L. 2015): 37-45. [3]
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