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Performing Non-Compartmental Analysis with Julia and Pumas AI

Domino Data Lab

Approximating the region under the graph of as a series of trapezoids and calculating the sum of their area (in the case of non-uniformly distributed data points) is given by. Having calculated AUC/AUMC, we can further derive a number of useful metrics like: Total clearance of the drug from plasma. Mean residence time. and many others.

Metrics 59
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Variance and significance in large-scale online services

The Unofficial Google Data Science Blog

by AMIR NAJMI Running live experiments on large-scale online services (LSOS) is an important aspect of data science. We must therefore maintain statistical rigor in quantifying experimental uncertainty. In this post we explore how and why we can be “ data-rich but information-poor ”.

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Experiment design and modeling for long-term studies in ads

The Unofficial Google Data Science Blog

Nevertheless, A/B testing has challenges and blind spots, such as: the difficulty of identifying suitable metrics that give "works well" a measurable meaning. accounting for effects "orthogonal" to the randomization used in experimentation. accounting for effects "orthogonal" to the randomization used in experimentation.

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LSOS experiments: how I learned to stop worrying and love the variability

The Unofficial Google Data Science Blog

Despite a very large number of experimental units, the experiments conducted by LSOS cannot presume statistical significance of all effects they deem practically significant. The result is that experimenters can’t afford to be sloppy about quantifying uncertainty. In statistics, such segments are often called “blocks” or “strata”.