Performing Non-Compartmental Analysis with Julia and Pumas AI
Domino Data Lab
DECEMBER 4, 2020
Having calculated AUC/AUMC, we can further derive a number of useful metrics like: Total clearance of the drug from plasma. NCA doesn’t require the assumption of a specific compartmental model for either drug or metabolite; it is instead assumption-free and therefore easily automated [1]. Mean residence time. and many others.
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