article thumbnail

Performing Non-Compartmental Analysis with Julia and Pumas AI

Domino Data Lab

Having calculated AUC/AUMC, we can further derive a number of useful metrics like: Total clearance of the drug from plasma. We can now pass the preprocessed data to the Pumas NCAReport function, which calculates a wide range of relevant NCA metrics. We can merge all the metrics in a separate DataFrame for further analysis.

Metrics 59
article thumbnail

Fundamentals of Data Mining

Data Science 101

Data mining is the process of discovering these patterns among the data and is therefore also known as Knowledge Discovery from Data (KDD). The models created using these algorithms could be evaluated against appropriate metrics to verify the model’s credibility. Regression.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Variance and significance in large-scale online services

The Unofficial Google Data Science Blog

Unlike experimentation in some other areas, LSOS experiments present a surprising challenge to statisticians — even though we operate in the realm of “big data”, the statistical uncertainty in our experiments can be substantial. Because individual observations have so little information, statistical significance remains important to assess.

article thumbnail

LSOS experiments: how I learned to stop worrying and love the variability

The Unofficial Google Data Science Blog

In this post we explore why some standard statistical techniques to reduce variance are often ineffective in this “data-rich, information-poor” realm. Despite a very large number of experimental units, the experiments conducted by LSOS cannot presume statistical significance of all effects they deem practically significant.