2006 Interactive Testing Uncertainty 
The Unofficial Google Data Science Blog
APRIL 23, 2024
Crucially, it takes into account the uncertainty inherent in our experiments. However, if we experiment with both parameters at the same time we will learn something about interactions between these system parameters. It is a big picture approach, worthy of your consideration.
The Unofficial Google Data Science Blog
MARCH 31, 2016
In the context of prediction problems, another benefit is that the models produce an estimate of the uncertainty in their predictions: the predictive posterior distribution. Column "a" is an advertiser id, "b" is a web site, and "c" is the 'interaction' of columns "a" and "b". $y$ Cambridge University Press, (2006). [2]
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